凝血酶治疗新生儿上消化道出血30例疗效观察

Therapeutic effect of thrombin on neonatal upper gastrointestinal hemorrhage: report of 30 cases

目的探讨凝血酶对新生儿上消化道出血的治疗效果。方法54例非血液病所致的新生儿上消化道出血患儿,随机分为2组,对照组24例采用常规止血治疗,凝血酶组30例在常规止血治疗基础上加用凝血酶治疗。结果治疗组的显效率(60.00%)和总有效率(93.33%)均明显高于对照组(显效率和总有效率分别为29.17%和66.67%,P均<0.05)。结论凝血酶治疗新生儿上消化道出血疗效可靠。

Objective To probe into the efficacy of thrombin in the treatment of neonatal upper gastrointestinal hemorrhage. Methods 54 cases of neonatal upper gastrointestinal hemorrhage without hematologic diseases were randomly assigned to 2 groups： the 24 cases in the control group were given the routine hemostatic treatment; to the 30 cases in the thrombin test group, thrombin was administered in addition to the routine hemostatic treatment. Results The market effective rate （60.00%） and the total effective rate （93.33%） in the thrombin test group were significantly higher than that of the control group （29.17% and 66.67% respectively, P 〈 0.05）. Conclusion The efficacy of thrombin in the treatment of neonatal upper gastrointestinal hemorrhage can be well recognized.