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重庆地区肝细胞癌p53基因突变类型的研究 被引量:3

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摘要 重庆地区肝细胞癌p53基因突变类型的研究肖文华刘为纹吕有勇李诤肝癌的病因存在明显的地区差别[1]。目前研究表明,突变是抑癌基因p53失活的重要机理[2,3]。肝癌p53基因突变存在2种类型:(1)突变散在于各外显子的散在型;(2)位点特异突变型。我们...
出处 《中华医学遗传学杂志》 CAS CSCD 北大核心 1997年第2期119-120,共2页 Chinese Journal of Medical Genetics
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参考文献2

  • 1肖文华,第三军医大学学报,1995年,17卷,1期,23页
  • 2Chang F,Am J Gastroenterol,1993年,88卷,2期,174页

同被引文献16

  • 1闵婕,冯英明,姬统理,李刚,宋扬,马宁强,王红玫.PCNA与P53蛋白在原发性肝细胞癌中的表达及意义[J].现代肿瘤医学,2004,12(6):516-518. 被引量:4
  • 2肖文华,刘为纹,吕有勇,高崇峰.肝细胞癌c-myc基因DNA甲基化模式的研究[J].中华医学杂志,1996,76(7):501-504. 被引量:12
  • 3Kirkwood JM, Tarhini AA, Panelli MC, et al. Next generation of immunotherapy for melanoma [ J ]. J Clin Oncol, 2008, 26: 3445 - 3455.
  • 4Harzstark AL, Small EJ. Immunotherapy for prostate cancer using antigen-loaded antigen-presenting cells: APC8015 (Provenge) [ J]. Expert Opin Biol Ther, 2007, 7:1275 -1280.
  • 5Ernstoff MS, Crocenzi TS, Seigne JD, et al. Developing a rational tumor vaccine therapy for renal cell carcinoma: immune yin and yang[ J]. Clin Cancer Res, 2007, 13:733 -740.
  • 6Naka T, Toyota N, Kaneko T, et al. Protein expression of p53, p21WAF1, and Rb as prognostic indicators in patients with surgically treated hepatocellular carcinoma[ J]. Antieancer Res, 1998, 18:555-564.
  • 7Svane IM, Pedersen AE, Johansen JS, et al. Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-6 as response biomarkers [ J ]. Cancer Immunol Immunother, 2007, 56 : 1485 - 1499.
  • 8Judith NC, Thomas S. Mobilization of autologous peripheral blood hematopoietic cells for support of high-dose cancer therapy[ M ] // Karl GB, Stephen JF, Frederick RA. Thomas'hematopoietic cell transplantation. 3th ed. Massachusetts: Blackwell Publishing Ltd, 2004 : 578.
  • 9Heiser A, Coleman D, Dannull J, et al. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors [ J ]. J Clin Invest, 2002, 109 : 409 -417.
  • 10Iwashita Y, Tahara K, Goto S, et al. A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer [ J ]. Cancer Immunol Immunother, 2003, 52 : 155 - 161.

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