重庆地区肝细胞癌p53基因突变类型的研究
被引量:3
摘要
重庆地区肝细胞癌p53基因突变类型的研究肖文华刘为纹吕有勇李诤肝癌的病因存在明显的地区差别[1]。目前研究表明,突变是抑癌基因p53失活的重要机理[2,3]。肝癌p53基因突变存在2种类型:(1)突变散在于各外显子的散在型;(2)位点特异突变型。我们...
出处
《中华医学遗传学杂志》
CAS
CSCD
北大核心
1997年第2期119-120,共2页
Chinese Journal of Medical Genetics
参考文献2
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引证文献3
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3张宏,肖文华,梁后杰.正反义人DNA(5-胞嘧啶)甲基转移酶基因片段真核表达载体的构建[J].癌症,2001,20(11):1325-1326. 被引量:4
二级引证文献4
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1肖文华,刘为纹.甲基化特异多聚酶链反应的改进及应用[J].癌症,2004,23(11):1354-1356. 被引量:3
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2张宏,肖文华,梁后杰,房殿春,杨仕明,罗元辉.人DNA MTase反义基因转染对肝癌细胞DNA MTase基因mRNA表达的影响[J].第三军医大学学报,2002,24(11):1264-1266. 被引量:3
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3张宏,肖文华,梁后杰,房殿春,杨仕明,罗元辉.人DNA MTase反义基因转染诱导E-Cadherin基因启动子区域去甲基化[J].第三军医大学学报,2002,24(11):1267-1269.
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4张宏,肖文华,梁后杰,房殿春,杨仕明,罗元辉.人DNA MTase反义基因转染对诱导肝癌SMMC7-721细胞凋亡的影响[J].第三军医大学学报,2002,24(11):1270-1272. 被引量:2
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1高子夜,刘晓波,骆志国.吉非替尼治疗不同EGFR突变类型非小细胞肺癌患者的疗效比较[J].海南医学,2017,28(7):1048-1050. 被引量:6
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2李艳菊,张春莉,尹香利,惠起源.结直肠癌KRAS基因突变检测及临床意义[J].延安大学学报(医学科学版),2015,13(2):45-46.
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