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临床试验之前的征程

The road ahead for trials
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摘要 在20世纪的后半叶,在各种情况下开发有效药物的研究范围发生了巨大的跨越。这些药物的问世已经毫无疑问地为挽救生命和减少疾病损失做出了重大贡献。不过,总的来说,这种进步的获得有赖于将注意力集中在大批已经被确诊的病人身上进行的临床试验。这种策略能确保即使试验药物不可能总是对每一个患者都起效,但至少对于患者的预期疗效而言还是安全的。 In the second half of the 20th century, enormous strides were made in the development of effective drugs for a wide range of conditions. These drugs have undoubtedly made major contributions to saving I disease. On the whole, however, yes and reducing the burden of this progress has been achieved by focusing on clinical tests on large groups of patients with precisely defined disease entities. The strategy ensured that drugs were safe relative to the expected benefits for the group, even if they were not always effective in every patient.
出处 《经济导报(医药技术)》 2007年第1期60-69,共10页
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