主动呼吸控制系统在肺癌放疗中的应用

The use of active breathing control in radiotherapy of lung cancer

目的:探讨主动呼吸控制(active breathing coordination,ABC)技术在肺癌精确放疗中的应用。方法:选取2006～2007年间来我科的12例肺癌患者,使用ABC技术联合三维适形放疗技术治疗,CT定位扫描时分别采集ABC和自由呼吸(free breath,FB)两套图像,计算比较两者胸壁动度、膈肌动度、大体靶区(gross tumor volume,GTV)、临床靶区(clinnical target volume,CTV)、计划靶区(planning target volume,PTV)及双肺V20、Dmean。结果:ABC状态下胸壁动度、膈肌动度、GTV、CTV、PTV及双肺V20、Dmean比FB状态下均要小,且差异有统计学意义(P<0.05)。结论:在肺癌的精确放射治疗中,ABC系统可以有效的降低呼吸运动对治疗的影响,提高放疗的精确性,减少副反应。

Objective：To discuss the application in accurate radio therapy of lung cancer using the active breathing control （ABC）.Methods：Choose 12 cases of lung cancer patients between 2006 and 2007 ,using of active breathing control in radiotherapy as a treatment technology.Each patient received computed tomography （CT） scans under two respiration ：free breath（FB）and active breath-hold.Comparisons differences in the chest wall and diaphragm mobility ,GTV, CTV,PTV, V20 and Dmax between ABC and FB plansy. Results ：Differences in the chest wall and diaphragm mobility,GTV,CTV,PTV, V20 and Dmax, between ABC and FB plans were significant （P〈0.05）.Conclusion ：In the precise radiotherapy of lung cancer,the ABC system reduced the influence of breathing,improved the precision of the radiotherapy and reduced the toxicity.