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格列美脲与格列吡嗪治疗2型糖尿病疗效比较 被引量:4

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摘要 目的比较格列美脲与格列吡嗪治疗2型糖尿病的疗效。方法将42例2型糖尿病患者随机分为格列美脲组与格列吡嗪组。格列美脲组20例,格列吡嗪组22例,观察时间12周。治疗前后监测病人空腹血糖(FBG)、餐后2小时血糖(2hPBG)、空腹胰岛素(FINS)、餐后2小时胰岛素(2hPINS)、糖化血红蛋白(HbA1c)、体重指数(BMI)。结果两组治疗前后FBG、2hPBG、HbA1c均明显下降(P<0.05),但两组相比差异无统计学意义;两组治疗前后FINS差异无统计学意义;格列美脲组2hPINS和BMI升高低于格列吡嗪组,差异有统计学意义(P<0.05),低血糖发生率显著低于格列吡嗪组(P<0.05)。结论格列美脲降糖效果好,使用安全。
作者 胡晓燕
出处 《内科》 2007年第5期779-780,共2页 Internal Medicine
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参考文献2

  • 1童南伟,梁荩忠.一种新的长效磺脲类降糖药:格列美脲[J].中国糖尿病杂志,2000,8(4):238-239. 被引量:22
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