4Mackensen S, Bullinger M. Development and testing of an instrument to assess the Quality of Life of Children with Haemophilia in Europe (Haemo-Qol.)[J]. Haemophilia, 2004,10 ( 1 ) : 17-25.
5Fischer K, Vanderbom J G.Vandenberg H M. Health-related quality of life as outcome parameter in haemophilia treatment[J]. Haemophilia, 2003,9( 1 ) : 75-82.
6Young N L,Bradley C S,Blanchette V. Development of a healthrelated quality of life measure for boys with haemophilia: the Canadian Haemophilia Outcomes-Kids Life Assessment Tool (CHO-KLAT)[J].Haemophilia, 2004,10 ( 1 ) :34-43.
7Mackensen S V. Qol. of life assessment from the point of view of a psychologist: how to develop a Qol. instrument, how to interpret its resuhs[J].Haemophilia,2006,12(s2):121-125.
8Gringeri A,Mantovani L, Mackensen S V. Quality of life assessment in clinical practice in haemophilia treatment[J]. Haemophilia,2006,12(3) :22-29.
9Bullinger M.Mackensen S V,Fischer K. Pilot testing of the ‘Haemo-Qol'quality of life questionnaire for haemophiliac children in six European countries[J]. Haemophilia, 2002,8 ( Suppl2 ) : 47-54.
10Scalone L, Mantovani L G, Mannucci P M. Quality of life is associated to the orthopaedic status in haemophilic patients with inhibitors[J].Haemophilia, 2006,12 ( 2 ) : 154-162.
4Lakich D, Kazazian HH, Antonarakis SE. Inversions disrupting the factorⅧ gene are a common cause of severe hemophilia A[J]. Nat Genet, 1993,5:236 - 241.
5Naylor J, Brinke A, Hassock S, et al. Characteristic mRNA abnormality found in half the patients with severe hemophilia A iS due to larger DNA inversions [J]. Hum Mol Genet, 1993,2 : 11,1773 - 1778.
6Sengupta B,De M,Lahiri P,et al.Sero-surveillance of transmissible hepatitis B & C viruses in asymptomatic HIV infection in haemophilics.Indian J Med Res,1992,95:256
7Wagner N,Rotthauwe HW.Hepatitis C contributes to liver disease in children and adolescents with hemophilia.Klin Padiatr,1994,206(1):40
