基底动脉病变患者预后及相关因素研究

Prognosis and Related Clinical Features in Patients with Basilar Artery Disease

目的研究基底动脉狭窄或闭塞所致后循环缺血患者的预后,分析与预后不良有关的临床特点。方法分析48例基底动脉中重度狭窄(狭窄率>50%)或闭塞患者的临床特点,随访患者病后3个月的情况,评估临床特点与预后不良的关系。结果病后3个月时预后不良患者19例,其中死亡4例。最常见临床表现为眩晕。发病72h内出现意识障碍者12例,有早期意识障碍者病后3个月时多预后不良(P<0.05)。结论基底动脉病变所致后循环缺血的预后并不象以往认为的那样差。眩晕是基底动脉病变的最常见临床表现,但与预后不良无明显相关。早期出现意识障碍可能提示预后不良。

Objective To study the clinical features and prognosis in patients with severe basilar artery disease.Methods The clinical features and damaged location in 48 patients with serious stenosis or occlusion in basilar artery were assessed and followed-up 3 months later.The correlation between the clinical features and poor outcome was analysed.Results 19 patients had poor outcome and 4 patients died during 3 months.The most patients suffered from vertigo attack.12 patients presented conscious disturbance within 72 h after onset,and most of them had poor outcome（P〈0.05）.Conclusion The prognosis of basilar artery stenosis or occlusive disease is not as grave as previously thought.Vertigo occurs frequently,but dose not relate with poor outcome significantly.Consciousness in the initial stage maybe relate to outcome significantly.