小儿恶性畸胎瘤SIL-2R测定的临床意义

The clinical significence of SIL-2R in children with malignant teratoma

目的:探讨 SIL-2R 与小儿畸胎瘤的关系。方法:采用 ELISA 对10例恶性畸胎瘤,12例良性畸胎瘤和24例正常儿童进行测定。监测 SIL-2R 与恶性畸胎瘤的预后关系。结果:恶性畸胎瘤组明显高于其它两组,P 值分别小于0.05和0.001,恶性畸胎瘤 SIL-2R 越高预后越差。结论:SIL-2R 对小儿恶性畸胎瘤的诊断、预后估计有参考价值。

Objective:To work out the relationship between SIL-2R and malignant teratoma. Methods:SIL-2R was determined by the ELISA method in 10 children with malignant teratoma, 12 children with benign teratoma and 24 normal controls.The relationship between the prognosis of malignant teratoma and the corresponding SIL-2R value was worked out.Results:SIL-2R in children with the malignant teratoma was higher than that in the other two groups(P<0.05,P< 0.01 respectively),and the higher the SIl-2R value was,the worse the prognosis of the malignant teratoma was.Conclusions:SIL-2R can be considered as a valuable factor in making diagnosis and prognosis of the malignant teratoma in children.