摘要
目的探讨Ⅰ期乳腺癌保乳手术时不行腋窝淋巴结清扫而术后根治性放疗的疗效。方法回顾性分析我科136例Ⅰ期乳腺癌临床资料,其中58例行保乳手术,术中不行腋窝淋巴结清扫,术后第1天开始用CMF方案化疗6周期,术后3周开始根治性术后放疗。78例行改良根治术,术后常规放化疗。结果保乳手术+腋窝放疗组与改良根治术组相比,二者在生存率及局部复发率上差异无统计学意义(P>0.05),而上肢水肿及功能障碍发生率差异有统计学意义(P<0.05)。结论Ⅰ期乳腺癌保乳手术并腋窝单纯放疗优于腋窝淋巴结清扫。
Objective To explore the eeffect of conservative surgery plus axillary radiotherapy in patients with stage Ⅰ breast cancer. Methods The date of 136 patients with stage Ⅰ breast cancer were retrospectively analyzed. 58 patients underwent conservative surgery and not received axillary surgery. After surgery, they received adjuvant chemotherapy with 6 pericdicities of CMF and radiotherapy. 78 patients received modified radical mastectomy, adjuvant chemotherapy and radiotherapy. Results There was no difference in recurrence rates and longterm survival between the two groups. But the frequency of arm edema and functional disturbance was significant difference between two groups. Conclusions The effect of conservative surgery plus axillary radiotherapy is preferable in patients with stage Ⅰ breast cancer.
出处
《肿瘤基础与临床》
2007年第5期415-417,共3页
journal of basic and clinical oncology
关键词
乳腺肿瘤
保乳手术
放射治疗
breast cancer
conservative surgery
radiotherapy
