多壁碳纳米管修饰玻碳电极伏安法测定氯霉素

Voltammetric Determination of Chloramphenicol Using Glassy Carbon Electrode Modified with Multi-wall Carbon Nanotubes

研究了氯霉素（CAP）在多壁碳纳米管修饰玻碳电极上的电化学行为.发现在pH=2.0的0.1 mol/LKCl-HCl底液中,CAP在该修饰电极上有一灵敏的还原峰（Ep=-0.36 V vs.Ag/AgCl）,峰电流与CAP浓度成正比,线性范围为6.0×10^-6~2.7×10^-4mol/L,检测限达3.0×10^-6mol/L.该方法灵敏、准确,用于模拟样品和实际样品的测定,结果满意.

A sensitive electrochemical method was developed for determination of chloramphenicol （CAP） using a glassy carbon electrode modified with multi-wall carbon nanotubes （MWNTs） film. In 0.1 mol/L KCl-HCl solution of pH 2.0, a sensitive cathodic peak of CAP on the MWNTs modified electrode was obtained at around - 0.36 V （vs Ag/AgCl）. Under the optimum conditions, the reduction peak current was linearly proportional with the concentration of CAP over the range of 6.0 × 10^-6 to 2.7 × 10^-4mol/L with a detection limit of 3.0 × 10^-6mol/L. The proposed method is sensitive and accurate, and can be applied to determine CAP in simulated samples and real samples with satisfactory results.