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VEGF-C在胃癌组织中的表达与淋巴管生成及淋巴结转移的相关性研究 被引量:5

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摘要 采用免疫组化S-P法检测20例正常胃组织、44例无淋巴结转移的胃癌组织和44例有淋巴结转移的胃癌组织中VEGF-C表达水平,分析其与微淋巴管密度(LMVD)、淋巴结转移的关系。结果示,VEGF-C在胃癌组织组的表达明显高于正常胃组织组(P<0.01);胃癌组织中VEGF-C的表达强度与微淋巴管密度(LMVD)有关(P<0.05);有淋巴结转移组胃癌组织的微淋巴管密度(LMVD)明显高于无淋巴结转移组(P<0.01);胃癌组淋巴结转移的数目与VEGF-C的表达强度有关(P<0.05)。提示:VEGF-C的表达与胃癌淋巴管生成及淋巴结转移关系密切;VEGF-C和微淋巴管密度(LMVD)是胃癌淋巴结转移的重要影响因素。
出处 《中国普通外科杂志》 CAS CSCD 2007年第9期915-918,共4页 China Journal of General Surgery
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参考文献14

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