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33例活体肝脏磁共振氢质子波谱分析 被引量:12

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摘要 使用1.5T磁共振仪对10例健康查体者(正常对照组)、20例肝硬化(肝硬化组)和10例肝癌(肝癌组)患者行磁共振氢质子波谱(^1H-MRS)分析。结果显示波谱检查成功率为82.5%(33/40),^1H-MRS图像由2个主要的代谢物波峰脂质峰群(Lip)和胆碱复合物峰(Cho)组成;正常组、肝硬化组、肝癌组Cho峰显示率分别为50%(5/10)、87%(13/15)、100%(8/8),且波峰高度逐渐升高;6例肝癌病灶于3.35~3.9 ppm检测到糖原/葡萄糖复合物峰(Glyu)。认为^1H-MRS可无创性显示肝脏疾病的生化和代谢改变,且正常肝组织、肝硬化和肝癌组织中代谢物波峰形态和数目不同,此可为肝硬化和肝癌的诊治提供理论依据。
机构地区 广东省人民医院
出处 《山东医药》 CAS 北大核心 2007年第23期67-68,共2页 Shandong Medical Journal
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参考文献6

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二级参考文献21

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