3～6岁儿童代谢综合征调查结果分析

The investigation result of 3～6 years old children with metabolic syndrome in Tianjin and its analysis

目的：随着儿童肥胖率的快速增长，成人慢性疾病在儿童时期的出现，儿童代谢综合征已引起人们的关注。本研究旨在掌握天津市3～6岁儿童代谢综合征检出情况并以此为依据制定相应的预防和治疗措施。方法：对肥胖组和对照组儿童进行代谢综合征相关指标的检测和测量，包括甘油三酯（TG）、高密度脂蛋白胆固醇（HDL—C）、血糖（GLU）及血压，比较两组儿童各指标水平和异常率，并统计天津市3～6岁儿童代谢综合征的检出率。结果：肥胖组儿童TG、GLU、收缩压（SBP）、舒张压（DBP）水平均高于对照组儿童，HDL—C水平低于对照组儿童，两组间差异有显著性；肥胖组儿童的TG、HDL—C、GLU、血压异常率均高于对照组儿童，两组问TG、血压差异有显著性。两组儿童代谢指标异常≥2项的人数共有64例，其中肥胖组52例，占肥胖组总人数的8．9％，对照组12例，占对照组总人数的1．7％，肥胖组异常人数所占比例是对照组的5．2倍。符合儿童代谢综合征诊断标准的有52例，占调查总人数的0．5％。结论：代谢综合征在儿童期就可以出现，在儿童期形成的危险因素是成年后早发心血管疾病、2型糖尿病等成人慢性疾病发生发展的重要潜在危险因素，只有有效地预防和治疗儿童肥胖，才能减少成人慢性疾病的发生和发展，这将是一项长期而艰巨的任务。

Objective： Along with the increasing of the children obesity, the adult chronic disease appears in the childhood, metabolic syndrome （MS） in children also begin to arouse peopleg interest. This research is aimed to investigate the 3 - 6 years old MS children in Tianjin so as to establish corresponding prevention and remedial measure. Methods： The interrelated index of MS in all of obesity group and control group, including triglyceride （TG）, high density lipoprotein cholesterol （HDL -C）, fasting blood glucose （FBG） and blood pressure were detected to compare various targets level and abnormal rate between two groups, and calculate its detective rate. Results： Levels of TG, FBG, systolic blood pressure （ SBP）, diastolic blood pressure （DBP） were significantly higher and HDL - C level was significantly lower in obesity group than those in control group; the abnormal rates of TG, HDL - C, FBG, blood pressure were higher in obesity group than those in control group, the difference of TG and the blood pressure between the two groups was significant. There were 64 cases of abnormal metabolism indexes≥2, 52 cases in obesity group, accounting for 8.9% ; 12 in control group, accounting for 1.7% ; obesity group had 5.2 times abnormal cases than control group. There were 52 cases consistent with the diagnosis standard of MS in children, accounting for 0.5% of the investigated population. Conclusion： MS could appear in the childhood time, these dangerous factor formed during the childhood could potentially lead to adult chronic disease such as blood vessel disease, type -2 diabetes mellitus and so on, only effectively prevents and treats obese children, can the occurrence and the development of adult chronic disease be reduced.