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健胃愈疡片治疗消化性溃疡临床疗效与安全性观察

An Evaluation on Clinical Efficacy and Safety of Jianwei-Yuyang Tablets in the Treatment of Peptic Ulcer
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摘要 目的:观察健胃愈疡片治疗消化性溃疡的临床疗效与安全性。方法:选择79例经确认的消化性溃疡患者,并采用中医辩证分型。观察每位用药者口服健胃愈疡片(1日4次,4-5片,次,共4周)前后的症状、体征及溃疡情况,评价疗效。结果:健胃愈疡片对消化性溃疡的主要证候胃脘痛、嗳气、返酸、嘈杂的有效率分别为:93.51%、90.00%、89.66%、87.10%;溃疡痊愈率为82.14%。对四种中医辩证分型证候的有效率:对肝郁脾虚的有效率为92.31%,对肝胃不和的有效率为90.63%,对脾胃虚寒有的效率为93.75%,对胃阴不足的有效率为80.00%。未发现与药物相关的不良反应。结论:健胃愈疡片治疗消化性溃疡疗效确切,安全可靠。 Objective:To observe the clinical efficacy and to evaluate the safety of Jianwei-Yuyang Tablets in the treatment of peptic ulcer. Methods: 79 patients who had been diagnosed as peptic ulcer and their aymptomatic types had been classified by the dialectical theory of Chinese traditional medicine were given Jianwei- Yuyang Tablets (4-5 patches, po, qid ) and the period lasted for four weeks. The curative effect of this medicine on peptic ulcer was observed and the safety was evaluated. Result:The efficiency rate of Jianwei-Yuyang Tablets was 82.14% on peptic ulcer. The recovery rate on main symptoms such as gastric abscess, belching, hyperchlorhydria and clatter was 93.51%, 90.00%, 89.66% and 87.10%, respectively. The rate of curative effect on depressed liver with the insufficient spleen, disharmony between the liver and stomach and insufficiency of the "spleen-yang" was 92.31%, 90.63% and 93.75%, respectively. No adverse events were observed. Condution: The Jianwei- Yuyang Tablets in the treatment of peptic ulcer are effective and safe in clinical practice.
作者 李爱国
出处 《药学进展》 CAS 2007年第9期424-426,共3页 Progress in Pharmaceutical Sciences
关键词 消化性溃疡 健胃愈疡片 临床疗效 安全性 Jianwei-Yuyang Tablets Peptic ulcer Efficacy Safety
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  • 1李家邦 陈国林 等.健胃愈疡片治疗胃、十二指肠溃疡的临床与实验研究[J].中西医结合杂志,1987,7(3):151-151.
  • 2Guth PH, Aures D, Paulsen G. Topical aspirin plus HCI gastric lesion in the Rat-cytoprotective effect of prostaglandin,cimetidine,and probanthine. Gastroenterology 1979; 76:88-93.
  • 3Ligumsky M, Sestieri M, Okon E, Ginsburg I. Antioxidants inhibit ethanol-induced gastric injury in the rat - role of manganese, glycine and carotene. Scand J Gastroenterol 1995;30:854-860.
  • 4周衍淑 赵轶干 王雨若.生理学方法与技术第2集[M].北京:北京科学出版社,1984.307-311.
  • 5Anggard E. Nitric oxide: mediator, murdere and medicine.Lancet 1994;343:1199-1205.
  • 6Mhlp S, Paula LH, Oliveira RB, Cunha FQ. Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor I(TNF-R1)or inducible nitric oxide synthase(iNOS) deficient mice. Gut 2004;53:791-796.
  • 7湖南医科大学.健胃愈疡片治疗消化性溃疡临床与实验研究[M].长沙:湖南九芝堂论文汇编,2003.
  • 8陈克勤 隆念组.健胃愈疡片治疗消化道溃疡病56例[J].中成药,2000,22(2):176-176.
  • 9广西医学科学情报所.疾病诊断标准[M].南宁:广西人民出版社,1983:280.
  • 10任俊杰,侯家玉,董秀云,李名沁,赵凤志,张燕平,董华,易凡,吴红梅.利胃复胶囊治疗痰瘀胃痛的临床及实验研究[J].中国中西医结合脾胃杂志,1997,5(3):151-153. 被引量:3

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