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血管内皮生长因子-D在胃癌转移中的作用 被引量：1

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摘要 血管内皮生长因子-D（VEGF-D）是近年来被发现的表达于淋巴管内皮细胞的特异性标志物，通过与VEGFR-2、VEGFR-3结合而发挥促血管、淋巴管生成的作用，临床上利用这一机制来控制胃癌的淋巴道转移。淋巴道转移是胃癌转移最重要的途径，淋巴结中肿瘤灶的出现常常是胃癌预后不良的最重要因素。作为淋巴管内皮细胞特异性标志物，VEGF-D在评价胃癌患者预后方面具有重要价值。现就VEGF-D的作用、机制、预后评价及治疗方面的进展作一综述。
作者 李竹林（综述） 朱明才 魏锦来（审校）
机构地区 重庆医科大学附属第一医院普外科 重庆市万州区三峡中心医院普外科
出处 《国际检验医学杂志》 CAS 2007年第9期826-828,共3页 International Journal of Laboratory Medicine
关键词 血管内皮生长因子 淋巴道转移 胃癌
分类号 R730.45 [医药卫生—肿瘤]
  • 相关文献

参考文献14

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共引文献22

同被引文献9

  • 1李杰,韩毅,刘志东,张海青,张宗德,岳文涛,贾红彦,许绍发,李宝兰.血管内皮生长因子-C和血管内皮生长因子-D在非小细胞肺癌中的表达与淋巴结转移关系的研究[J].中华临床医师杂志（电子版）,2011,5(13):3763-3767. 被引量：2
  • 2王凯峰,叶胜龙,宋丽杰,翁永强,梁春敏,赵燕,高东梅,汤钊猷.不同转移潜能的小鼠肝癌淋巴道转移和淋巴管生成的研究[J].中华肝脏病杂志,2006,14(3):187-191. 被引量：7
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国际检验医学杂志
2007年 第9期

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