摘要
目的HPLC法测定经带宁胶囊中丹皮酚的含量。方法色谱柱：KromasilC18（150mm×4．6mm，5μm）；流动相：甲醇：水（60：40）；流速：1．0mL·min^-1；检测波长：274nm。结果丹皮酚在12．72-127．20μg·mL^-1范围内呈线性关系，平均回收率99．26％，RSD=1．2％（n=6）。结论该方法简单、可靠、专属性强，可用于经带宁胶囊的质量控制。
OBJECTIVE To determine the content of Paeonol by RP-HPLC in Jingdaining Capsules. METHODS The HPLC system consisted of Kromasil C18 column（150mm ×4.6mm, Stem）. The flow rate was 1ml · min^-1 and the detective wavelength was 274nm. RESULTS The calibration curve was linear in the range of 12.72-127.20μg·ml^-1 for Paeonol. The average recovery was 99.26%. RSD =1.2%（ n =6）. CONCLUSION The HPLC method is simple,reliable,specific,and can be used for the quality control of Jingdaining capsules.
出处
《齐鲁药事》
2007年第9期533-534,共2页
qilu pharmaceutical affairs
