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丙泊酚联合小剂量氯胺酮用于小儿无痛胃镜检查术 被引量:1

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摘要 目的观察丙泊酚联合小剂量氯胺酮用于小儿无痛胃镜检查术的临床效果。方法50例需行无痛胃镜检查术的患儿,随机分为两组,每组25例。Ⅰ组按氯胺酮1 mg.kg-1单次静脉注射后,再复合丙泊酚静脉注射。Ⅱ组丙泊酚静脉注射。待患儿入睡,睫毛反射消失后开始进镜。退镜时停止给药。监测两组患儿的平均动脉压(MAP)、心率(HR)、脉搏氧饱和度(SPO2),记录麻醉起效时间、手术时间、停用麻醉药后睁眼时间以及丙泊酚的用量,并观察呼吸抑制的例数。结果两组患儿生命体征的变化差异无显著性,麻醉起效时间、手术时间、睁眼时间相似,但丙泊酚的用量Ⅰ组比Ⅱ组显著减少,呼吸抑制病例Ⅰ组也少于Ⅱ组。结论丙泊酚联合小剂量氯胺酮用于小儿无痛胃镜检查术是一项安全有效的麻醉方法,它可减少丙泊酚用量,降低呼吸抑制的发生率,不延长苏醒时间。
出处 《医药导报》 CAS 2007年第10期1181-1182,共2页 Herald of Medicine
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