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膳食营养素摄入与前列腺癌 被引量:1

Relationship between Dietary Nutrients intakes and Human Prostate Cancer
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摘要 为探讨膳食营养素与前列腺癌的关系,对102例前列腺癌患者进行了1∶1配比的病例对照研究。根据近三月食物摄入量的平均值计算蛋白质、脂肪、糖类等11种营养素及总执量的日平均摄入量,采用配对t检验和条件Logistic回归分析。结果表明:脂肪、糖类、视黄醇当量等的摄入量大能增加前列腺癌的危险性,维生素C、维生素B1等能降低其危险性,各营养素的多变量调整OR值及95%可信区间分别为脂肪1.65(1.39~1.96)、碳水化合物1.22(1.13~1.31)、视黄醇当量3.12(2.18~4.75)、维生素C0.61(0.46~0.80)、维生素B10.029(0.009~0.09)。本文还对各营养素增加或降低前列腺癌危险性的可能机制进行了讨论。 In order to study the relationship between dietary nutrients intakes and prostate cancer,1∶1 matched case control study was carried out with 102 patients suffered from histologically confirmed prostate cancer and 102 healthy controls.Total calories and 11 nutrients including protein,lipid and carbohydrates were calculated based on the mean food intakes in the latest 3 days.Analyzed by matched t test and conditional logistic regression method,the results showed that high intakes of lipid,carbohydrates,and retinol increased the risk of prostate cancer,but vitamin C and vitamin B 1 decreased the risk of prostate cancer.The multi variable adjusted ORs were 1 65(95% confident interval(CI)1 39~1 96) for lipid,1 22(95% CI 1 13~1 31)for carbohydrates,3 21(95% CI 2 18~4 75)for retinol,0 61(95%CI 0 6~0 80) for vitamin C,and 0 029(95% CI 0 009~0 09)for vitamin B 1.The authors discussed the possible mechanism of dietary nutrients contributing to the risk of prostate cancer.
出处 《卫生研究》 CAS CSCD 北大核心 1997年第2期122-125,共4页 Journal of Hygiene Research
基金 国家教委博士研究生课题
关键词 前列腺癌 维生素A 维生素C 脂肪 肿瘤发生 prostate cancer retinol vitamin C fat
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