莫沙比利联合多虑平治疗功能性消化不良106例疗效分析

Effect Observation of Therapeutic Alliance of Functional Dys-pepsia with Mosapride and Doxepin

目的评价莫沙比利和多虑平联合治疗功能性消化不良的疗效。方法将106例功能性消化不良患者随机分为治疗组和对照组，分别用莫沙比利和多虑平联合治疗与莫沙比利单独治疗，疗程均为4周。结果莫沙比利和多虑平联合治疗组症状明显改善，有效率82.7％，莫沙比利组有效率仅为57.4％（P〈0.01）。结论莫沙比利多虑平联合治疗功能性消化不良疗效较好，不良反应小，不影响肝肾功能，病人易于接受。

Objective To Evaluation Efficacy of therapeutic alliance of functional dyspepsia with Mosapride and Doxepin. Methods 106 patients with functional dyspepsia were divided into two groups at random, the therapeutic alliance group treated by Mosapride and Doxepin, control group treated by Mosapride only, Course of treatment was 4 weeks, Results The therapeutic alliance group treated by Mosapride and Doxepin symptoms showed obviously amelioration. Effective power was 82,7%,the group treated by- Mosapride only was 57.4%（P〈0.01）,Conclusion Mosapride and Doxepin therapeutic alliance functional dyspepsia curative effect was better, Adverse reaction was small, Don＇t effect liver renal function. Patients ible to accept.