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抑癌基因PTEN与胃癌相关性研究进展 被引量:3

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出处 《吉林医学》 CAS 2007年第12期1347-1349,共3页 Jilin Medical Journal
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  • 1[1]Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH,Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R,Swedlund B, Teng DH, Tavtigian SV. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997; 15:356-362
  • 2[2]Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J,Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC,Ittmarn M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. PTEN,a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275:1943-1947
  • 3[3]Li DM, Sun H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 1997; 57:2124-2129
  • 4[4]Cantley LC, Neel BG.New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci U S A 1999; 96: 4240-4245
  • 5[5]Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL. The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 1998; 95:15587-15591
  • 6[6]Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,trisphosphate and Akt/protein kinase B signaling pathway.Proc Natl Acad Sci U S A 1999; 96:6199-6204
  • 7[7]Maehama T, Taylor GS, Dixon JE. PTEN and myotubularin: novel phosphoinositide phosphatases.Annu Rev Biochem 2001; 70: 247-279
  • 8[8]Besson A, Robbins SM, Yong VW. PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. Eur J Biochem 1999; 263: 605-611
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  • 10[10]Tanno S, Tanno S, Mitsuuchi Y, Altomare DA, Xiao GH, Testa JR. AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells. Cancer Res 2001; 61:589-593

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