4Lin Yang Li-Ge Kuang Hua-Chuan Zheng Jin-Yi Li Dong-Ying Wu Su-Min Zhang Yan Xin No.4 Lab,Cancer Institute,The First Affiliated Hospital,China Medical University,Shenyang 110001,China Ying Chen Shen Yang Gynecology & Obstetrics Hospital,Shenyang 110014,China.PTEN encoding product:a marker for tumorigenesis and progression of gastric carcinoma[J].World Journal of Gastroenterology,2003,9(1):35-39. 被引量:127
1[1]Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH,Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R,Swedlund B, Teng DH, Tavtigian SV. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997; 15:356-362
2[2]Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J,Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC,Ittmarn M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. PTEN,a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275:1943-1947
3[3]Li DM, Sun H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 1997; 57:2124-2129
4[4]Cantley LC, Neel BG.New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci U S A 1999; 96: 4240-4245
5[5]Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL. The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 1998; 95:15587-15591
6[6]Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,trisphosphate and Akt/protein kinase B signaling pathway.Proc Natl Acad Sci U S A 1999; 96:6199-6204
7[7]Maehama T, Taylor GS, Dixon JE. PTEN and myotubularin: novel phosphoinositide phosphatases.Annu Rev Biochem 2001; 70: 247-279
8[8]Besson A, Robbins SM, Yong VW. PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. Eur J Biochem 1999; 263: 605-611
9[9]Waite KA, Eng C. Protean PTEN: form and function. Am J Hum Genet 2002; 70:829-844
10[10]Tanno S, Tanno S, Mitsuuchi Y, Altomare DA, Xiao GH, Testa JR. AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells. Cancer Res 2001; 61:589-593
5Jing L,Clifford Y,Danny L,et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and proetate cancer [ J ]. Science, 1997,275 (5308) : 19435.
6Li DM, Sun H. TEP1, encoded by a candidate tumor suppreasor locus, is a novel protein tytosine phoaphatase v%qdated by transforming growth factor - beta [ J ]. Cancer Res, 1997,57 (11) : 2124.
7Steck PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumor suppressor gene MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers [ J ]. Nat Genet, 1997,15(4) :356.
8Mofimoto AM, Berson AE, Fujii GH, et al. Phenotypic analysis of human glioma cells expressing the MMAC1 tumor sup- pressor phosphatase [ J ]. Oncogene, 1999,18 : 1261.
9Tamura M, Gu J, Takino T, et al. Tumor suppressor PTEN inhibition of cell invasion, migration and growth:differential involvement of focal adhesion kinase and p130Cas [ J ]. Cancer Res, 1999,59(2) :442.