人正常精子形态率对辅助生殖治疗结局的影响

Influence of Human Normal Morphology Sperm Rate on Assisted Reproductive Therapy Outcome

目的:探讨人正常精子形态率对IVF或ICSI治疗结局的影响。方法:观察70周期正常精子形态率对IVF或ICSI后受精率、卵裂率、胚胎冷冻率、种植率、妊娠率及流产率的影响。结果:(1)精子形态异常组,精子的活动率和活动力也显著降低。(2)精子形态正常组IVF受精率、卵裂率显著高于异常组,而IVF的冷冻胚胎率、种植率、妊娠率、流产率及ICSI结局的各项指标两组间均无显著差别。结论:正常精子形态率对IVF受精率、卵裂率有显著影响,而对IVF或ICSI其他治疗结局尚无明显相关。

Objective：To analyse the influence of human normal morphology sperm rate on IVF or ICSI outcome. Methods ： Fertilization, cleavage, embryo cryopreservation, plantation, pregnancy and abortion rates of 70 couples were observed to study the influence of human normal morphology sperm rate on IVF or ICSI outcome. Results ： （1）When the normal morphology sperm rates were significantly low,the sperm motility parameters were significantly decreased. （2） IVF fertilization and cleavage rates in normal sperm morphology group were significantly higher than those in abnormal group, while both IVF and ICSI embryo cryopreservation ,plantation,pregnancy and abortion rates ,even ICSI fertiliza- tion and cleavage rates in two groups were all not found significantly different. Conclusion：There is a significant influ- ence of human normal morphology sperm rate on IVF fertilization and cleavage rates and no significant influence on other outcomes of IVF or ICSI.