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ATⅡ受体拮抗剂对AMI后患者长期抗缺血及降低缺血事件的作用

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摘要 目的:观察血管紧张素(AT)受体拮抗剂减少急性心肌梗死(AMI)后患者心肌缺血及其相关事件的影响。方法:将87例AMI后患者随机分为43例服用缬沙坦治疗组和44例常规治疗对照组,于出院前、出院后3、6、12个月行Hotter心肌缺血总负荷检测(TIB),并观察缺血相关事件。结果:于出院后1 a,治疗组TIB及缺血相关事件明显少于对照组,但出院后前6个月随访观察两组差异并不明显。结论:AT受体拮抗剂对AMI后患者具有长期的抗缺血和减少缺血事件的作用。
作者 苑林
出处 《中国误诊学杂志》 CAS 2007年第24期5744-5745,共2页 Chinese Journal of Misdiagnostics
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  • 1Levi A,Claudis PP,Li Q,et al.Stretch-mediated release of angiotension Ⅱinduces myocyte apoptosis by activiating P53 that enhances the local renin-angiotension system and decreases the bcl-2 to box protein ratio in the cell[J].J Clin Invest,1998,101:1326-1343.
  • 2Dzau VJ,Sasamura H,Hein L.Heterogeneity of angiotensin synthetic pathways and receptor subtypes:physiological and pharmacological implications[J].J Hypertens,1993,11:513.
  • 3Min Nian,Paul Lee,Neelam Khaper,et al.Inflammatory cytokines and postmyocardial infarction remodeling[J].Circ Res,2004,94:1543-1553.
  • 4Hiroaki Matsubara.Pathophysiological Role of Angiotensin Ⅱ Type 2 Receptor in Cardiovascular and Renal Diseases[J].Circulation Research,1998,83:1182-1191.
  • 5Kober L,Torp-Pedersen C,Carlsen JE,et al.A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction.Trandolapril Cardiac Evaluation (TRACE) Study Group[J].N Engl J Med.1995,333:1670-1676.
  • 6The AIRE Study Investigators.Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure.The acute infarction ramipril efficacy (AIRE) study investigators[J].Lancet,1993,342:821-828.
  • 7Pfeffer MA,Braunwald E,Moye LA,et al.On behalf of the SAVE Investigators[J].N Engl J Med,1992,327:669-677.
  • 8Ambrosioni E,Borghi C,Magnani B.The effect of the angiotensin-converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction[J].N Engl J Med,1995,332:80-85.
  • 9GISS-3I.Six-month effects of treatment with lisinopril and transdermal glyceryl trinitrate singly and together withdrawn six weeks after acute myocardial infarction[J].J Am Coll Cardiol,1996,27:337-344
  • 10ISIS-4 Collaborative Group.ISIS-4:A randomised factorial trial assesing early oral captopril,oral mononitrate,and intravenous magnesium sulphate in 58050 patients with suspected acute myocardial infarction[J].Lancet,1995,345:669-685.

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