107例婴儿口服脊髓灰质炎疫苗的成功率与哺乳关系的研究

Study Out the Relationship of Successful Administrating of Poliomyelitis Vaccine by Infaust and the Breast Feeding

目的研究婴儿口服脊髓灰质炎疫苗(糖丸)的成功率与哺乳后间隔时间的关系,探讨哺乳后对口服糖丸的影响。方法将107例2～5月龄的婴儿分为3组,分别在哺乳后0.5h、1h、1.5h后喂服糖丸,并观察喂服后的反应。结果哺乳后0.5h喂服糖丸与1.5h后再喂服,其反应强度有差异(P<0.05)。结论婴儿口服糖丸的成功率与哺乳后间隔的时间有关。哺乳后间隔的时间与喂服糖丸的成功率成正相关。哺乳后1.5h是喂服糖丸的最佳间隔时间。

OBJECTIVES To study the connection between effectiveness of the poliomyelitis vaccine and interval after breast-feeding for infants, and to explore the how breast feeding affect oral administration of poliomyelitis vaccine. METHODS 107 infants aging 2 to 5 months were divided into 3 groups, and were gave poliomyelitis vaccines orally 0.5 hour, 1 hour and 1.5 hours after breasting feeding, respectively, and observe the responses thereafter. RESULTS Intensity of response was different between infants taking poliomyelitis vaccine 0.5 hour and 1.5 hours after breast-feedning, respectively （P〈0.05）. CONCLUSION Breast feeding is related to success of oral administration of poliomyelitis vaccine, interval after breast-feedning has positive co-relation with oral administration of poliomyelitis vaccine. 1.5 hours after breast-feedning is optimal time to take oral administration of poliomyelitis vaccine.