1Marcellin P, ChangTT, Lam SG, et al. Adefovir dipivoxil for the tream ent of hepatitis B eantigen-postitive chronic hepatitis B [J] . N EnglJM ed, 2003, 348(9): 808-816.
2Angus P, Vaughan R, Xiong S, et al.Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV poly merase[J]. Gastroenterology, 2003, 125(2): 292-297.
10Koskinas J, Manesis EK, Kountouras D, et al. Adefovir dipivoxil alone or in combination with lamivudine in HBeAg negative patients with lamivudine resistant chronic hepatcis B: a prospective, randomized study[J] ,Hepatology,2005,42(Suppl 2): 18l.
