人偏肺病毒感染的认识和研究

Recognition and Study of Human Metapneumovirus

人偏肺病毒(HMPV)是一种单链负链RNA病毒,属于副黏病毒科,是最近被发现的一种致病性病毒。病毒感染的流行在各个地区不同,同一个流行季节可以有两个病毒谱系流行。感染后可以导致上、下呼吸道感染和喘息性疾病,在儿童和免疫力低下的群体中往往导致严重呼吸道感染,可与其他病毒合并感染,隐性感染少见。目前检测HMPV感染的主要方法是逆转录-聚合酶链反应,尚无一种抗病毒药物或者疫苗能够有效治疗和预防HMPV感染。

Human metapneumovirus （HMPV） is a recently found virus with pathogenicity, which is a single and negative strand RNA virus belonging to paramyovirus. Viral infection is has different epidemic in different area,of which two virous pedigree can have its epidemic in the same epidemic season. Its infection can result in upper or lower respiratory infection and gasping disease, even severe respiratory infection in children people with hypoimmunity, of which the infection often has concurrent infection of other viruses, while inapparent infection is seldom. The main method detecting HMPV is reverse transeriptase-polymerase chain reaction （RT-PCR）. There is still no anti-virus drugs or vaccine to effectlvey cure and prevent the infection of HMPV.