四黄水蜜外敷合加味四妙散内服治疗急性痛风性关节炎的临床研究

A Clinical Research of Jiawei Simiaosan Oral Administration Combined With the External Application of Sihuangshuimi in the Treatment of Acute Gouty Arthritis

目的:探讨中医传统疗法治疗急性痛风性关节炎的临床疗效。方法:将65例符合急性痛风性关节炎患者随机分为治疗组与对照组,治疗组以加味四妙散内服及四黄水蜜外敷,对照组以秋水仙碱口服,进行为期一周的治疗观察。根据临床症状、实验室指标进行评分,评价疗效。结果:两组疗效相当(P>0.05),两组患者治疗前后症状和体征积分及实验室指标的变化,除对照组的血尿酸治疗前后无明显变化外(P>0.05),其余指标均较治疗前有明显改善(P<0.01)。治疗组血尿酸下降水平优于对照组(P<0.05)。结论:四黄水蜜外敷合加味四妙散内服治疗急性痛风性关节炎能起到降体温、消肿止痛、改善关节功能、降低血尿酸的作用。

Objective：To investigate the clinical curative effect in the treatment of acute gouty arthritis with Chinese traditional medicine. Methods ： All the 65 patients of acute gouty arthritis were randomly divided into two groups. The treatment group was treated by jiawei simiaosan and combined with the external application of Sihuangshuimi. The control group was treated by gclchicine. Then an evaluation was made on the clinical effect just referring to clinical symptoms and physical sign after a week. Results ：Two groups were therapeutic equivalence （P 〉 0. 05 ）. The changes of the two groups in clinical symptoms ,physical signs and integral signs were so obvi- ously after treatment （ P 〈0.01 ） ,except for the UA of control group （ P 〉 0.05 ）. Howerer, the level of UA of the treatment group had an advantage to the control group （P 〈 0. 05 ）. Conclusion：The effect of using sihuangshuimi combined with jiawei simiaosan to cure acute gouty arthritis is not only to improve joint function and cut down UA level obviously,but also to decline the body temperature and decrease swelling to relieve pain.