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葛根煎剂对四氧嘧啶致糖尿病小鼠血糖及其并发症的影响 被引量:5

Effects of Pueraria lobata on Blood Sugar and Complications of Alloxan-induced Diabetes Mice
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摘要 以四氧嘧啶致小鼠建立糖尿病模型,经葛根煎剂灌胃,连续35 d,每周测定空腹血糖和体重;小鼠在灌胃结束后,断头处死,分别取其胰腺和肾脏做切片进行检查。结果显示:葛根煎剂对糖尿病模型小鼠空腹血糖水平有一定的降低作用,但作用强度较弱;能改善小鼠体质的作用;对肾病并发症有较好的疗效,对被破坏的胰岛细胞有恢复和修复作用。 A rat model of alloxan-induced diabetes was intragastrically administered with Pueraria lobata for 35 days. And the blood sugar and weight of the rats were detected once a week. After the intragastrical administration, the rats were killed and their kidneys and pancreas were sliced up for further investigation. Results showed that the Pueraria lobata extract had relative low capability of reducing the blood sugar, while could improve the constitution of the rats. Besides, the Pueraria lobata extract showed better curative effect of kidney complications of the diabetes rats and could repair the alloxan-destructed pancreas islet cells.
作者 贺筱蓉
出处 《现代食品科技》 EI CAS 2007年第10期32-33,共2页 Modern Food Science and Technology
关键词 葛根煎剂 糖尿病 小鼠 四氧嘧啶 pueraria lobata diabetes mouse alloxan
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  • 1李光伟,Step.,L.检测人群胰岛素敏感性的一项新指数[J].中华内科杂志,1993,32(10):656-660. 被引量:2125
  • 2曹守仪,李宝华.同时测定小鼠抗缺氧和耗氧量的简便实验方法[J].中国药理学通报,1995,11(1):85-86. 被引量:15
  • 3王开贞.党参的抗缺氧作用[J].中药通报,1986,11(8):53-55.
  • 4冯亦璞 孙亚丁 等.小鼠脑缺血后的能量代谢改变和药物作用[J].药学学报,1989,24(2):89-94.
  • 5冯亦璞,药学学报,1989年,24卷,2期,89页
  • 6王开贞,中药通报,1986年,11卷,8期,53页
  • 7Shankland S J, Scholey JW. Expression of growth-related protooncogenes during diabetic renal hypertrophy. Kidney Int1995; 47: 782-8.
  • 8Murphy M, McGinty A, Godson C. Protein kinase C: potential targets for intervention in diabetic nephropathy. Curr Opin Nephrol Hypertens 1998; 7: 563-70.
  • 9Koya D, King GL. Protein kinase C activation and the development of diabetic complications. Diabetes 1998; 47: 859-66.
  • 10Pariat M, Salvat C, Bebien M, Brockly F, Altieri E, Carillo S, et al. The sensitivity of c-Jun and c-Fos proteins to calpains depends on conformational determinants of the monomers and not on formation of dimers. Biochem J 2000; 345: 129-38.

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