辽宁农民体重指数 腰围与脑卒中患病关系的流行病学调查

Epidemiological survey on waist circumference, body mass index and their relevance to stroke morbidity in Liaoning rural areas

目的探讨辽宁农村地区人群腰围(WC)、体重指数(BMI)与脑卒中患病率的流行病学关系,评价超重及肥胖对脑卒中的危害程度。方法采用分层整群随机抽样的方法,按统一标准对辽宁农村35岁及以上常住人口45,925人进行流行病学问卷调查并体检。以不同WC和BMI分层,计算脑卒中患病率。使用Epidata3.1软件建立数据库,SPSS11.5软件包进行统计分析。结果脑卒中患病平均年龄较大,多有高血压病史。65岁以下各年龄组,随着WC和(或)BMI的增加,脑卒中患病率明显升高。分层分析发现,在多数BMI分层各组中,WC与脑卒中患病率呈线性相关(线性趋势检验P<0.01)。多因素相关回归分析,WC与脑卒中的相关性较强,最小OR值>1,差异有统计学意义。结论随着超重、肥胖人群比率的增加,辽宁农村中老年人群脑卒中患病率上升,二者有独立的关联性。控制超重、肥胖尤其是向心性肥胖是脑卒中预防的重点。

Objective To investigate body mass index （BMI）, waist circumference （WC） and their influence on stroke morbidity of peasants in epidemiology. Methods The large and random sample population-based cross-sectional survey involved a total of 45 925 adult peasants in Liaoning rural areas, in forms of questionnaire and on-the-spot physical examination. Stroke diagnosis was made by specialists＇ staff depending on the patient＇s history, physical check up and cerebral CT results, and stroke morbidity were counted at different level of BMI and WC. Software SPSS11.5 was introduced to statistical analysis, with data pool established in Epidata 3.1. Results The survey study showed that stroke patients were a little older. With BMI and WC increasing, there were much more stroke occurrence. In most BMI level groups, it prevailed close line correlations between WC and stroke morbidity （line trend test, P 〈 0.01 ）. The multiple variant regression analysis showed the close relevance between them either, with the lowerrest OR value above 1 and marked statistical difference. Conclusion BMI and（or） WC raising would increased stroke risk in northeast rural areas, in all age groups, except in age ≥65 years. The former should be considered as important independent predictors of stroke. Reducing overweight and obesity,especially central adiposity, and trying to keep BMI and WC at normal level might effectively cut down stroke morbidity.