甲亢性周期性瘫痪30例临床分析

Clinical Analysis of 30 Cases of Thyrotoxic Periodic Paralysis

目的探讨以低钾性瘫痪为主要临床表现的甲状腺功能亢进症(甲亢)的发病相关因素及治疗方法。方法对30例甲亢性周期性瘫痪(TPP)的临床资料进行回顾性分析。结果发作时均有不同程度双下肢或四肢瘫痪;T3、T4均高于正常。结论甲亢性周期性瘫痪以年轻男性多见,补钾短期内可改善TPP症状,抗甲亢治疗是预防TPP复发的关键。

Objective To investigate the pathogenic related factor of hyperthyroidism with clinical manifestation of low potassium paralysis and its regimen. Methods The clinical data of 30 patients with thyrotoxic periodic paralysis （TPP） were analysed. Results All 30 patients had different paralysis of bilateral lower limbs or four limbs in the onset of TPP and accompanied with the blood K^＋ decrease.The values of T3 and T4 in all patients were higher than those in normal people. Condusion The male patients with thyrotoxic periodic paralysis are mere than female patients. Replenishing K^＋ can shortly ameliorate the symptom of thyrotoxic periodic paralysis, and the anti-hyperthyroidism therapy is key to control the recurrence of thyrotoxic periodic paralysis.