期刊文献+

胰岛素强化治疗对应激性高血糖症炎症介质的影响 被引量:1

下载PDF
导出
摘要 将86危重病患者以随机数字表法分为胰岛素传统治疗组和胰岛素强化治疗组,采用放射免疫分析或双抗体夹心酶联免疫吸附法测定开始治疗前、治疗后72 h肿瘤坏死因子(TNF-α)、人可溶性TNF受体Ⅰ(sTNFRⅠ)、Ⅱ(sTNFRⅡ)、sFas以及sFasL的水平。结果显示,治疗后胰岛素强化治疗组sTNFRⅡ水平明显低于胰岛素传统治疗组(P<0.05);TNF-α、sTNFRⅠ和sTNFRⅡ均随病情的缓解而下降(P均<0.05)。认为胰岛素强化治疗可以改善危重症合并应激性高血糖症患者的预后。
出处 《山东医药》 CAS 北大核心 2007年第27期99-100,共2页 Shandong Medical Journal
  • 相关文献

参考文献4

二级参考文献36

  • 1毛旭虎,许霖水.胰岛素受体酪氨酸蛋白激酶在重度烫伤大鼠胰岛素抵抗中作用的研究[J].第三军医大学学报,1996,18(1):1-4. 被引量:14
  • 2Svanfeldt M, Thorell A, Brismar K,et al.Effects of 3 days of ""postoperative"" low caoric feeding with or without bed rest on insulin sensitity in healthy subjects[J]. Clin Nutr,2003,22(1):31-38.
  • 3Yamauchi T,Kamon J, Waki H,et al. The fat-derived houmone adiponectin revese insulin resistance associated with both lipoatrophy and obeity[J]. Nat Med,2001,7(8):941-946.
  • 4Leinskold T, Adrian TE, Arnelo V,et al. Gastrointestinal growth factors and pancreatic islet hormones during postoperative IGF-1 supplementation in man[J]. J Endocrinol,2000,167(2):331-338.
  • 5Antti Virkamaki, Kohjiro Veki, C Ronald Kahn. Protein-protein interaction in insulin signaling and moldcular mechanisms of insulin resistance[J]. Clin Invest,1999,103(7):931-943.
  • 6LeRoith D, Zick Y. Recent advances in our understanding of insulin action and insulin resistance[J]. Diabetes Care,2001,24:588-597.
  • 7Tsuneya Ikezu, Takashi Okamoto, Kazuyoshi Yonezawa,et al. Analysis of Thermal Injury-induced Insulin Resistance in Rodents[J]. The American Society for Biochemistry and Molecular Biology,1997,272(40):25289-25295.
  • 8B.L.GrEgoie Nyomba, Lori Berard, Liam J,et al. Free Insulin-Like Growth FactorⅠ(IGF-Ⅰ) in Healthy Subjects:Realationship with IGF-Binding Proteins and Insulin Sensitivity[J]. The Journal of Clinical Endocrinology &amp; Metabolism,1997,82(7):2177-2181.
  • 9Tsao TS, Stenbit AE, Factor SM,et al. Prevention of insulin resistance and diabetes in mice heterozygous for GLUT-4 ablation by transgenic complemention of GLUT-4 in skeletal muscle[J]. Diabetes,1999,48(4):775-782.
  • 10Boden G, Chen X, Ruiz J,et al. Insulin receptor down-regulation and impaired antilipolytic action of insulin in diabetic patients after pancreas/kidney transplantation[J]. J Clin Endocrinol Metab,1994,78(3):657-663.

共引文献59

同被引文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部