新生儿胃食管返流的24小时食管内pH监测

Gastroesophageal reflux in neonates: 24-hour intraesophageal pH monitoring

目的探讨新生儿胃食管返流食管内pH的变化及其临床意义。方法疑诊为新生儿胃食管返流36例，以无症状新生儿15例作对照。用便携式24小时食管、胃pH自动记录仪（Digitrapper型）在常态下作24小时食管内pH监测。食管pH降至4以下持续15秒钟以上定义为一次返流。结果疑诊为新生儿胃食管近流的36例中14例Boix－Ochoa评分＞11．99为病理性返流，22例为生理性返流。15例对照组中2例为生理性返流，13例为正常。结论24小时新生儿食管内pH监测为早期诊断新生儿胃食管返流提供客观依据。

Objectives To study lower esophageal pH changes and its clinical value in neonates with gastroesophageal reflux (GER).Methods Thc distal esophageal monitoring was per formed using a Synectics Digitrapper Systenl for ambulatory pH rccording. Each period longer than 15 seconds during which the pH<4. 0 is defined as a reflux episode. Thirty-six cases suspected GER were done and 15 asymptomatic newborn served as controls.Results The results showed that 22 cases of 36 were physiologicaI reflux and 14 cases pathological reflux according to Boix -Ochoa score more than 11. 99 and acid reflux index more than 10% while 2 of 15 controls to be physiological reflux and the other 13 remained normal.Conclusions The results indicated that 24-hour esophageal pH monitoring should be considered as the most reliable way for early diagnosis of neonatal GER.