我院抗菌药物临床应用调查分析

Clinical Application of Antibiotics in Our Hospital: Survey and Analysis

目的:促进临床合理应用抗菌药物。方法:对我院2005年4 186份出院病历的抗菌药物应用情况进行回顾性分析。结果:我院抗菌药物应用率达64.48%,其中预防性用药占56.17%,无指征用药占5.89%;抗菌药物占药品总数的45.90%;医院感染率为4.16%,其中真菌感染占23.56%;不良反应发生率为2.56%。结论:我院临床预防性应用抗菌药物的比例偏高,可导致耐药菌株及医院感染的发生,应加强管理。

OBJECTIVE： To promote the rational use of antibiotics.METHODS： A retrospectively analysis was conducted on the application of antibiotics in 4 186 discharge case histories in 2005.RESULTS： Of the total 4 186 cases, the application rate of antibiotics was 64.48% ,among which, 56.17% were prophylactic use of antibiotics and 5.89% used antibiotics without indication. The consumption of antibiotics occupied 45.90% of the total medicines consumed. The nosocomial infection rate was 4.16%, of which, 23.56% were fungous infections .The incidence of adverse drug reactions was 2.56% .CONCLUSION： The rate for the prophylactic use of antibiotics in our hospital is on the high side,which may result in high incidences of drug resis tant strains and nosocomial infections, therefore,measures should taken to tight the control of the administration of antibiotics.