我院2006年药品不良反应报告回顾性分析

ADR Case Reports: Retrospective Analysis of 144 Cases in Our Hospital in 2006

目的:推进我院药品不良反应(ADR)监测报告工作的开展。方法:对我院2006年收集到的144例ADR报告进行统计、分析。结果:涉及ADR的药品76种,其中抗感染类药物引起的ADR占总例数的44.4%(64例),抗肿瘤类、神经系统类和中药制剂类药物引起的ADR也较多;静脉途径给药的ADR占70.8%(102例),是引起ADR的主要途径;ADR涉及的器官或系统主要为皮肤及其附件。结论:临床科室应重视ADR的监测和报告工作,以减少和避免ADR的发生。

OBJECTIVE： To facilitate the monitoring and reporting of ADR.METHODS： A total of 144 ADR case reports collected in 2006 were analyzed statistically.RESULTS： The drugs that induced ADR totaled 76 kinds.Of the 144 ADR cases, 44.4% （64 cases） were induced by anti- infective drugs, followed by antitumor drugs, nervous system medicines and Chinese drugs preparations; 102（70.8% ） were induced by intravenous injection .Lesions of skin and its appendages were the chief clinical manifestations of the ADR.CONCLUSION： In order to reduce and avoid the occurrence of ADR, clinical departments should attach great importance to the monitoring and reporting of ADR.