被动吸烟对孕鼠及其胚胎的影响

Affect of passive smoking to two generation mice

利用母体-胎儿这一特殊联系，探讨了被动吸烟对两代小鼠的危害。研究结果表明，整个孕期被动吸烟，窝胎仔数为7．4，与孕6天后被动吸烟（窝胎仔数为12．6）及对照组（窝胎仔数为12．1）差异显著（P＜0．01）。被动吸烟对孕鼠及其胎鼠嗜多染红细胞微核率亦有明显增加作用，实验组分别为6．06‰及3．2‰，与对照组比较差异显著（P＜0．01）。

The harmfulness of passive smoking to two generations mice was proposal using the special maternal-fetal relationship. The results showed that in comparsion with the group of passive smoking after the sixth day of gestational period and the control group (the number of one brood fetus were 12. 6 and 12. 1, respectively), the group of passvie smoking in whole gestational period (the number of one brood fetus was 7.4) had significant difference (P<0.01). The paper also showed that the passive smoking had an obvious action for increasing the micronucleus percent of polychromatic erythocytes of pregnant mice and her fetus, and the two micronucleus percent of the experimental groups were 6.06‰ and 3.2‰, respectively, significantly different with the control group's (P<0.01).