激光散射光谱对胃癌治疗过程的监测作用

Study on the scattering spectrum in monitoring therapeutical process of the stomach carcinoma

对359例不同病期不同病理类型的胃十二指肠恶性肿瘤病人及50名非癌病人进行胃液的激光散射光谱的研究。发现在470nm光散射峰的强度胃十二指肠恶性肿瘤病人是非癌病人的4～10倍，平均7倍。术前259例，阳性率达93％以上；术后85例，转阴率达84．7％，复发胃癌15例，阳性率86．66％。不同病理类型的胃十二指肠恶性肿瘤之间，阳性率无显著差异（P＞0．05）。术后仍呈阳性者为三期及四期胃癌行姑息手术者。因此，激光散射光谱可作为胃十二指肠恶性肿瘤治疗过程的监测手段。

The paper reports to reseach in laser scattering spuctrum of 359 patients with gestric and duodenal malignent tumour that is different pathophysiological classification and cancer stage and of 50 patients with noncancer by gastric juice. Discovered that in 470nm scattering spectrum gastric and duodenal carcinoma was 4~10 times higher than in the noncancer. Positive rate of 259 patients be fore operation is 93%, negative rate of 85 patients after operation is 84. 7%. Positive rate is found to be 86.6%in 15 recurrent gastric cancer cases. For gastric and duodenal cancer that belong to different pathophysiological classification, the difference of positive rate wasn't markedly significant (P>0.05). It is the third and fouth stage of gastric cancer processed with palliative operation that appear positive even after operation. It would be a nice monitoring method during cure of gastric and duodenal cancer.