高危人群慢性支气管炎与肺癌关系的研究

A Cohort Study on the Relationship of Chronic Bronchitis and Lung Cancer among a High risk Population

本文应用前瞻性队列研究方法，探讨了慢支史与肺癌发生的联系。结果显示：慢支史与肺癌的发生有联系，相对危险度２．０左右；慢支史暴露的病因分值约５０％，说明慢支致肺癌的病因作用不容忽视；分析没有发现慢支史与粉尘、砷、氡子体暴露及吸烟间有相乘的交互作用关系。

A prospective Cohort study were conducted (1992￣1994) among a high risk population to explore the relation of chronic bronchitis and lung cancer.The result of study showed that there was association between lung cancer incidence and chronic bronchitis adjusted by other risk factors(RR=2.0).The aetiological fraction of the history of chronic bronchitis was about 50%.The study illustrates that chronic bronchitis was very likely to be an important cause of lung cancer.There was no statistically significant interaction between chronic bronohitis and dust,arsenic,radon and smoking exposure.