我国食管癌二级预防的Meta-analysi

Using Meta analysis on Secondary Prevention of Esophageal

本文通过检索《中文科技资料目录》及文献追溯的方法，共收集食管癌二级预防有关文献９篇，其中一篇未设对照组，三篇数据重叠，实际分析文献５篇，试验组共３９０２例，对照组２２４０例。Ｍｅｔａ－ａｎａｌｙｓｉｓ方法采用随机效应模型即Ｄ－Ｌ法，该模型假定各研究提供不同的真实作用的估计，考虑各研究间的变异，以研究内和研究间方差和的倒数为权重进行合并分析。结果表明７个使用中草药预防食管癌发生的研究，合并ＯＲ点估计值为０．３５９，９５％可信区间为０．２５０～０．５１５，可见食管上皮重度增生患者服用中草药可以降低约６０％的发病危险，从而进一步证实了食管癌二级预防的效果。

This paper was summarized using Meta analysis on the secondary prevention of esophageal for 10 Chines documents.The consequence indicated that the combination OR=0 359,CI:95%=0 250￣0 515,in the 7 studies of the traditional Chinese herbs.It was suggested that Chinese herbs could decrease about 60% of the risk of esophageal in the patients of serious epithelial hyperplasia of esophagus.