11例新生儿沙眼衣原体感染的诊断及临床分析

CHLAMYDIAL TRACHOMATIS INFECTION OF NEWBORN:DIAGNOSIS AND CLINICAL ANALYSIS OF 11 CASES

本文旨在新生儿先天性感染中进行沙眼衣原体病原学及临床研究。采用间接血凝试验（IHA）、间接免疫荧光法血清抗体定量测定（IIFA），荧光标记单克隆抗体咽、眼分泌物抗原检查（micro－IF）及聚合酶链反应（PCR）。对128例患者进行沙眼衣原体测定，结果发现沙眼衣原体感染率为8.59％（11／128例）。临床主要表现为新生儿肺炎和结膜炎。给予氨苄青霉素或羟氨苄青霉素治疗疗效较好。提出沙眼衣原体在新生儿感染中应予以重视。

Etilogy and clinical study of chlamydial trachomatis (CT) were perfornled in newbrons with congenital infection. 128 cases were measured for CT by tneans of indirect hemagglutination, indirect immunofluorescent assay, oligoclonal antibody marked by micro-immunofluorescence to measure the antigen of pharynx and eye secretion, and plymerase chain reaction, respectively. The results showed that the infection rate of CT was 8. 59 %. Pneumonia and conjunctivitis of newbron were the main clinical character. Ampicillin or amoxycillin were effective in the treatment of the newborn infected by CT