摘要
对31例新生儿硬肿症进行了血清超氧化物歧化酶(SOD)、丙二醛(MDA)和维生素E(VE)的测定并与21例正常新生儿对照。结果发现,硬肿患儿SOD活性明显低于对照组(P<0.001),并且下降程度与硬肿程度相关;MDA含量明显高于对照组(P<0.05),但与硬肿程度无明显关系;VE含量低于对照组,但无统计学差别。硬肝患儿经抗氧化剂和东莨菪碱治疗后硬肿消失的时间分别是5.22±1.40天和4.86±1.72天,两种方案的治疗效果无明显差别(p>0.05)。
We measured superoxide dismutase (SOD), malonylaldehyde (MDA) and vitamin E (VE) in 31 neonatal sclerema patients and 21 normal neonates. The results showed that the level of SOD was lower in sclerema group than that of control group (P<0.001), furtherrnore the severer of sclerema the lower of SOD. On the contrary the level of MDA was higher in patients than that of control group (P<0.05). The level of VE decreased in sclerema patients, but no statistics difference- After treatment by VE or scopolamine , 27 patients recovered. The peroid of sclerema disappear were no significance between two groups
出处
《新生儿科杂志》
1997年第2期55-57,共3页
The Journal of Neonatology