东菱克栓酶治疗老年急性脑梗死55例分析

Batroxobin For Senile Acute Cerebral Infarction(Report of 55 Cases)

目的:观察东菱克栓酶(DF-521)治疗老年急性脑梗死的早期疗效。方法:110例老年急性脑梗死患者随机分为两组,观察组(n=55)使用DF-521,每次5BU加入0.9%盐水100ml,静脉1h滴完,首次剂量加倍,隔日1次,一般用3次,长者5次。对照组(n=45)给脉络宁及胞二磷胆碱静脉点滴治疗,每日1次。结果:治疗14d后进行疗效判定,观察组总有效率为92.73%,对照组为68.89%,P<0.01。结论:DF-521治疗老年急性脑梗死早期疗效好,且安全,值得在老年急性脑梗死治疗中推广应用。

Objective：To observe the early effect of batroxobin（DF-521） on senile acute cerebral infarction.Methods： 110 senile cases of acute cerebral infartion were randomly divided into two groups： observation group with DF-521（n=55） in dose of 5BU in 100ml saline every two days for 3 times;control group with intravenous mailuoning and citicoline transfusion daily.Results： After treatment for a period of 14 days,the total effective rate was 92.73% in observation group,68.89% in control group（P〈0.01）.Conclusion：It is considered that DF-521 is effective and safe in early treatment of senile acute cerebral infarction. It should be recommended in treatment of senile acute cerebral infarction.