冠心病痰瘀证的微观辨证研究

Study on the Microcosmic Differentiation of Phlegm-Retention Syndromes of Coronary Heart Disease

目的探讨冠心病痰瘀证的微观辨证。方法运用临床流行病学调查方法,观察冠心病患者的中医证型分布,分析冠心病痰瘀辨证与血糖、胰岛素、血脂、血液流变学指标的相关性。结果血脂异常是痰凝心脉证的物质基础,血液流变学指标异常是痰瘀痹阻证的物质基础,胰岛素抵抗存在于冠心病的各证型,且按非痰非瘀证→痰凝心脉证→痰瘀痹阻证的顺序有逐渐加重的趋势。结论冠心病痰瘀证与血脂、血液流变学的异常及胰岛素抵抗密切相关。

Objective To study the microcosmic differentiation of phlegm-retention syndromes of coronary heart disease. Methods The clinical epidemiological investigation method was applied to observe the TCM syndrome distribution of coronary heart disease and to analyze the relation between the phlegm-retention syndrome of coronary heart disease and the blood sugar, insulin, blood fat and hemorheology indices. Results The abnormal blood fat was proved to be the material base of the syndrome of phlegm-retention in heart vessels; the abnormal hemorheological index was proved to be the material base of the syndrome of phlegm-retention obstruction. The insulin resistance existed in all syndromes of coronary heart disease, and the gradual aggravation tendency was from no phlegm-retention to phlegm-retention in heart vessels and to phlegm-retention obstruction. Conclusion The phlegm-retention syndromes of coronary heart disease are closely related to the abnormal blood fat and hemorheology and the insulin resistance.