重组人生长激素对机械通气患者氧合的影响

Effect of rhGH on Oxygenation of patients with mechanical ventilation

为了探讨重组人生长激素(rhGH)对机械通气治疗危重患者的治疗效果,将31例机械通气治疗的危重患者随机分为rhGH组和对照组,rhGH组每晚皮下注射rhGH8IU,连续记录7d内的各项指标。结果显示,rhGH组机械通气时间明显短于对照组,差异有统计学意义;rhGH组患者APACHEⅡ评分于用药后第5天开始明显低于对照组;对用药不同阶段氧合指标的比较,两组患者氧分压指标的变化差异统计学意义,而应用rhGH组患者呼吸指数和氧合指数于用药后第5天和第7天明显高于对照组,有统计学意义。因此,应用rhGH可以促进机械通气的危重患者自主呼吸功能的恢复。

To discuss the effect of rhGH on the critical patients with mechanical ventilation 31 patients in ICU with mechanical ventilation were randomly divided into rhGH group and control group, rhGH group 8IU rhGH IH QN for 7 days. The period of rhGH group with mechanical ventilation were obviously shorter than the control group. There was significant difference between two groups. The APACHE Ⅱ score of rhGH group were significantly lower than the control group after 5 days of the treatment. There were no difference PaO2 between the two group. The respiratory Index and the Oxygenation Index were higher than the control group in 5th 7th day. The rhGH can improve the recovery of spontaneous breathing, of the patients with mechanical ventilation.