猪瘟病毒生物学特性研究概述

Studies on Biological Characteristics of Classical Swine Fever Virus

阐述了猪瘟病毒与机体免疫系统的相互作用、在哺乳动物细胞中的增殖特点、与毒力相关基因的预测。概括了世界猪瘟病毒的基因分型、不同基因型毒株的分布情况和流行病学,分析了病毒的遗传变异特点与疫苗免疫前景,讨论了消灭猪瘟要面临的问题。

The biological characteristics of classical swine fever virus was expatiated in the paper. The interaction of classical swine fever virus（CSFV） with immune system of swines, CSFV prolifera-tion characteristics in mammalian cells and the prediction of genes associated virulence were mainly elucidated. The genotyping of CSFV and its distribution and epidemiology in the world were generalized. The genetic mutation of CSFV and the prospect in vaccine immunization have been analyzed. The problems of eradicating CSFV faced in future were also discussed.