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蛋白多肽类药物微球鼻腔给药的研究进展 被引量:4

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摘要 鼻腔给药是指在鼻腔内使用,发挥局部和全身作用的给药系统。鼻腔给药可避开“首过效应”,药物吸收迅速.可提高生物利用度,部分药物生物利用度可接近于静脉给药。是一种非侵入性给药方式,使用方便。患者依从性好。
出处 《中国药物与临床》 CAS 2007年第10期737-739,共3页 Chinese Remedies & Clinics
基金 国家自然科学基金资助项目(30371781)
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参考文献20

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  • 5郑爱萍,于少云,赵莹,武凤兰.鼻用氟尿嘧啶壳聚糖微球的制备及其特性研究[J].北京大学学报(医学版),2004,36(3):300-304. 被引量:20
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二级参考文献6

  • 1Willim MP. Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems[J]. Pharm Sci Technol Today,1999:49-51
  • 2Illum L. Transport of drugs from the nasal cavity to the central nervous system[J]. Eur J Pharm Sci,2000, 11:1-18
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  • 6Emad EH, Roy CP, James MG. Optimized Formulation of Magnetic Chitosan Micropheres Containing the Anticancer Agent, Oxantrazole [J]. Pharm Res,1992,9:390-397

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二级引证文献24

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