特发性少精子症与精索静脉曲张少精子症生殖内分泌及睾丸病理研究

A COMPARATIVE STUDY OF ENDOCRINOLOGY AND TESTICULAR PATHOLOGY BETWEEN IDIOPATHIC OLOGOZOOSPERMIA AND VARICOCELE CAUSED OLIGOZOOSPERMIA

对25例特发性少精子症、20例精索静脉曲张少精子症及57例对照进行了血生殖激素测定、睾丸体积测量及活检标本病理分析。发现特发性少精子症者的FSH水平较精索静脉曲张者的升高更为显著，而LH及T水平无显著差异。二类少精子症者的睾丸体积、曲细精管直径及管壁厚度无明显差异，但精索静脉曲张者曲细精管内细胞脱落严重并伴有间质水肿及小血管病变，而特发性少精子症者曲细精管内生精低下明显。精索静脉曲张者的Silber曲线理论精子密度明显少于实际精子密度，提示有睾丸内梗阻因素存在。

25 cases of idiopathic oligozoospermia and 20 cases of varecocele caused oligozoospermia were compared in the aspects of sex endocrinology, testicular pathology. Serum FSH level in thegroup of idiopathic oligozoospermia was markedlyhigher than that in the group of varicocele caused ollgozoospermia，while LH and T levels showed respectively no significant difference between the two groups．No significant differences were found of testicular volume， the diameter and membrane of seminiferous tubules between the two groups．But varicocele caused oligozoospermia had obvious germ cell exfoliation accompanied with interstitial edema and vessel changes while the idiopathic oligozoospermiahad distinct hypospermatogenesis． The calculatedsperm density was significantly higher than the actual one in the group ofvaricocele caused oligozoospermia，which suggested that there was luminalobstruction in testicels．