交变磁场治疗紧张型头痛临床对照研究

Clinical case control study of tension headache treatment with Transcranial Magnetic Stimulation

目的：探讨交变磁场对紧张型头痛的治疗疗效。方法：将138例紧张型头痛患者随机分成两组，治疗组给予交变磁场治疗，40rain/日。对照组给予阿米替林25～50mg/日。治疗4周后，对疗效进行评定，并采用SDS、SAS、SCL-90、GQOLI进行评定。结果：治疗组有效率为91．7％，对照组有效率为66．7％，两组比较有非常显著性意义（x^2=42.34，P＜0．001），且焦虑、抑郁、症状自评及生活质量量表两组均有改善。结论：交变磁场治疗紧张型头痛疗效好，不良反应小，是一种有效的治疗方法，值得临床进一步推广。

Objective：To explore the efficacy of Transcranial Magnetic Stimulation （TMS） on tension headache. Methods： One hundred and thirty eight patients with tension headache were randomized to TMS group and control group treated with amitriptyline （25 - 50 mg per day） for 4 weeks. SDS, SAS, SCL - 90, and GQOL were used for outcome measures. Results ： The effective rate of TMS group was significantly higher than that of control group （91.7% and 66.7% , respectively ）. Two groups showed improvements in anxiety, depression, and quality of life. Conclusions： TMS proved to be an aid in the treatment of tension headache.