更昔洛韦滴眼液治疗流行性急性角结膜炎的临床对比研究

A clinical control study of therapeutic effect of gutta ganciclovir on epidemic acute keratoconjunctivitis

目的:研究更昔洛韦滴眼液对流行性急性角结膜炎的临床疗效。方法:采用随机双盲的方法,将流行性急性角结膜炎患者随机分为2组,分别使用更昔洛韦滴眼液与阿昔洛韦滴眼液进行治疗,8次/日,治疗8天,观察两组患者的治疗效果。结果:82例完成本研究,更昔洛韦滴眼液治疗组总有效率明显高于B组,差异有显著性(P<0.05)。结论:更昔洛韦滴眼液是一种安全有效的治疗流行性急性角结膜炎的药物,同阿昔洛韦滴眼液相比,更昔洛韦滴眼液治疗流行性急性角结膜炎更有效。

Objective：To investigate the therapeutic effect of gutta ganciclovir on epidemic acute keratoconjunctivitis. Meth- ods：Using a scheme of random and double - blind, cases with epidemic acute keratoconjunctivitis were randomly divided into two groups to accept either 0.1% gutta ganciclovir, or 0.1% gutta acyclovir treatment for 8 days. And observe the therapeutic effect of 0. 1% gutta ganciclovir and 0.1% gutta acyclovir to two groups cases. Results： There were statistically significant difference of treatment efficacy between the 0. 1% gntta ganciclovir treatment group and 0. 1% gntta acyclovir treatment group. Conclusions： The results showed that the topical ganciclovir was an effective and safe antiviral agent in the treatment of epidemic acute keratoconjunctivitis and was better than gntta acyclovir to treatment epidemic acute keratoconjunctivitis.