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阳离子脂质体的转染机制及转染效率影响因素 被引量:24

The Mechanism and Efficiency Affecting Factor of Cationic Liposome Transfection
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摘要 阳离子脂质体是一种非常具有发展前景的基因载体。简要介绍了阳离子脂质体的结构特点;着重讨论了阳离子脂质体作为基因载体时介导基因转移的机制以及在转染过程中对基因转染效率产生影响的主要因素。  Cationic liposome is a greatly promising gene carrier.In this paper,the structure trait of cationic liposome was briefly introduced,the mechanism of cationic liposomes mediated gene delivery and the main influencing factor of transfection efficiency in the transfection process were discussed chiefly.
出处 《生物工程学报》 CAS CSCD 北大核心 2007年第5期776-780,共5页 Chinese Journal of Biotechnology
关键词 阳离子脂质体 基因治疗 转染机制 转染效率 cationic liposome,gene therapy,transfection mechanism,transfection efficiency
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  • 1邱仁宗.2001高技术发展报告[A]..第五章生物技术对社会的影响[C].北京:科学出版社,2001.132.
  • 2[1]Dienstag JL,Schiff ER,Mitchell M,et al.Extended Lamivudine retreatment for chronic hepatitis B[J].Hepatology,1996,24(1):188
  • 3[2]Muller RH,Mader K,Gohla S.Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art[J].Eur J Pharm Biopharm,2000,50(1):161
  • 4[3]Hashida M,Nishikawa M,Takakura Y.Hepatic targeting of drugs and proteins by chemical modification[J].J Controlled Release,1995,36(1/2):99
  • 5[4]Muller RH,Mehnert W,Lucks JS.Solid lipid nanoparticles (SLN)- an alternative colloidal carrier system for controlled drug delivery [J].Eur J Pharm Biopharm,1995,41:62
  • 6[5]Muller RH,Maassen S,Schwarz C.Solid lipid nanoparticles(SLN) as potential carrier for human use: interaction with human granulocytes[J].J Control Release,1997,47:261
  • 7[6]Muller RH,Ruhl D,Runge S,et al.Mehnert W.Cytotoxicity of Solid lipid nanoparticles as a function of the lipid matrix and the surfactant [J].Pharm Res,1997,14:458
  • 8[7]Schearz C,Mehnert W,Lucks JS,et al.Solid lipid nanoparticles (SLN) for controlled drug delivery.ⅠProduction,charecterazation and sterilization[J].J Control Release,1994,30(1):83
  • 9Walters L. The ethics of human gene therapy. Nature, 1990; 320:225-227.
  • 10Federal Ret, ister 58(197) : 53248-53251. Thursday. 1993;14:93N-0173.

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