口腔颌面颈部恶性淋巴瘤病理细胞分型与预后的关系(附75例报告)

Correlation between Tumor Cell's Classification and Prognosis in Malignant Lymphoma of the Oral Maxillofacial and Neck Region

75例口腔颌面及颈部恶性淋巴瘤采用了化学治疗.分析了瘤细胞分型与化疗效果及预后之间的关系.4例非何杰金淋巴瘤中滤泡型音:中细胞型2例,混合细胞型及大细胞型各1例,五年生存率皆为100%,显示其预后良好.弥漫型的细胞分型及五年生存率:小细胞型为 15.3%(13例),中细胞型为23%(13例),混合细胞型为18.7%(16例),显示其预后较差.而大细胞型(8例)、淋巴母细胞(10例)、巴基特型(1例)等五年生存率皆为0%,显示这些肿瘤预后极差.本组10例何杰金氏淋巴瘤,其中淋巴细胞为主型2例,结节硬化型3例,其五年生存率皆为100%;混合细胞型(4例)为50%,淋巴细胞消减型(1例)五年生存率为0%.

75 cases with malignant lymphoma in the oral maxillofacial and neck regions were treated by chemotherapy, and the correlation between the effects of chemotherapy (prognosis) and the classification of lymphoma was analysed. There were 4 cases of non-Hodgkin's lymphoma of follicular type:medium-sized cell type 2 cases, mixed cell and large cell type 1 case each. The five year survival rate of these 4 cases was 100% and showed a excellent prognosis. In diffuse pattern of lymphoma, the five year survival rate were 15. 3%(13 cases) in small cell type, 23%(13 cases) in medium-sized cell type and 18. 7%(16 cases) in mixed cell type, which showed a relatively poor prognosis, and in large cell type (8 cases), lymphoblastic type (10 cases) and Burkit's lympoma (1 cases), their five year survival rate were all 0% and showed that the prognosis of these tumors was very poor. In our series, there were 10 cases of Hodgkin's lymphoma. The five year survival were 100% in lymphocytic predominant type (2 cases) and nodular sclerosing type (3 cases), 50% in mixed cellularity type (4 cases) and 0% in lymphocytic depletion type (1 cases) respectively.