双歧杆菌微胶囊喷雾干燥工艺的影响因素研究

Effect Factor of Spray Drying Technology on Microencapsulation of Bifidobacteria

选择明胶为壁材,以两歧双歧杆菌(Bifidobacterium bifidus)Bbm为实验菌株,采用喷雾干燥的方法制成徽胶囊。研究了喷雾干燥过程中的固形物浓度、进样流量、进风温度、出口温度对微胶囊产率及菌体存活率的影响,确定最佳操作工艺参数为:固形物浓度为3%,进样流量为360 mL/h,进风温度为105℃,出口温度为54～57℃,微胶囊产率为65.7%,活菌存活率为53.5%,活菌数超过1×10^(10)cfu/g。

Gelatin was chosen for the wall material. The best technical conditions for spray drying of Microencapsulation of Biffdobacteria were determined according to the experiment. The results show that the best concentration of wall-material is 3% ,inlet air temperature and outlet air temperature are 105℃. and 54℃ -57℃ respectively,inlet flow rate is 360 mL/h. Under the optimized conditions, the rate of productivity and survival bacterium are 65.7% and 53.5℃ respectively. The number of survival bacterium is over 10^10 cfu/g.